I've had a few bouts with RTN, not any major event after a water change, but a random incident here and there.
In the few cases that I caught, it was total devastation, or would have been if I didn't frag them. I find that if I can frag the coral before the infection reaches the fragged pieces, they will survive. It truly seems to be a creeping infection that moves fast and kills/eats what it touches.
The big (once) beautiful purple 5" digi (now a skeleton) in the center of this picture melted in just hours.
I managed to frag off several tips. A few weeks later, they're doing fine. The 5 or so purple digi frags in this picture were saved from the above colony mid-incident. There are actually a couple of broken tips still sitting on the sandbed that I still need to get glued to a plug.
So, my rookie advice based on just a few cases is to cut your losses, literally, and frag whatever can be saved. Cut far enough away from the infection so you know it's clean.
That also allows you to get the infected tissue out of the tank.