I have a closed loop on my tank, which has similar dimensions to the one you are talking about (mine is 6x3x2.5). I'd definitely agree -- no closed loop. Not that mine has really caused any problems...I just think you can accomplish what you generally want in most tanks without it and save some money too boot (on electricity at least, although the ampmaster I use is better than many).
My tank is viewable on three sides and I think the closed loop helps me in that regard. The two outlets come up from the bottom towards the 'far' (viewable) end of the tank (intake is in the overflow), and then tee off so there are actually four outlets. It all helps me get different flow at that end of the tank that would be challenging to achieve (nicely) without a closed loop.
My return goes through an octopus to eight different locations (four coming in through the overflow wall and four coming down from pipes that run along the euro-bracing and dump at the surface)...but my two Tunze Streams are probably the 'dominant' flow.
I really like the flow patterns in the tank...nothing incredibly strong and a great mix that isn't purely uni-directional.
I like the idea of using the overflows to hide the powerheads and wish I had thought about doing that when I spec'ed my tank out. The good news to remember though is that with the depth you are talking about (3-4') I really can't see how your focus would ever be on those pumps with everything else in the tank!
Speaking of depth, it is awesome having at least 3'...but I'd say only 3'. Anything more and you can't reach the center of the tank very well at all.
I have a 30" depth which visually I prefer, but from a maintenance standpoint a 24" depth is soooooo much easier. I'm 6' tall and it is a ROYAL PITA to reach the bottom of my tank, and nearly impossible in the middle area. I'd probably still go 30" though because visually it is so much nicer.
Anyway, I still think the 'perfect' tank is 8x3x2.5 and if you absolutely cannot go 8', then I'd do 7' 12". ;-) But 6' is pretty nice too.
Have you started designing the fishroom already?